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The ChemiScreen β1 Adrenoceptor Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of ADRB1 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
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Kupffer cells are the resident macrophages in the liver and are part of the first line of defense against bacteria and toxins in the gut Kupffer cells exhibit typical macrophage morphology and can be activated to produce inflammatory cytokines growth factors and reactive oxygen species In vivo prolonged activation of Kupffer cells are associated with many diseases of the liver including non-alcoholic fatty liver disease (NAFLD) non-alcoholic steato hepatitis (NASH) and liver damage associated with certain bioactivated chemicals Human Cryopreserved Kupffer cells are isolated and enriched from dissociated human liver tissue and then cryopreserved as passage 0 Characterization of isolated Kupffer cells includes assessing morphology in plated format and evaluating functional responses to LPS stimulation
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More